This is an open book examination. You may use your notes and any avaiable printed material but please do not consult staff members or other students.
The exams are to bo turned in by 5:00 pm, December 13, 1961.
1. Prepare a compact guide (not more that three pages) to recommend procedures for acquisition, processing and utilization of quantitative bio-medical or biophysical data.
2. Prepare a somewhat detailed résumé of the means by which we “see” structure in biological systems in the microscope and submicroscope ranges from 2 Å to 20,000 Å and by which we infer quantitative details of such structures. You may, if you want, go beyond material discussed in class, e.g. X-ray diffraction electron microscopy, etc., but you need not. Please try to emphasize the widely varied (optical contrast and visualization) means by which we get at such structures and try to offer an example here and there of ways we get at such structures and try to offer an example here and there of ways in which such observations are made to yield quantitative measurements to yield quantitative data.
3. Fake the experimental results of a polarization miscropy experiment in which you determine something relating to the molecular organization of a biological material, e.g. Protein such as myosin, keratin, phospholipids, polysaccharides, etc. in say a tissue such as kidney, nerve or muscle and in which you make quantitative measurement of birefringence by the Newton color methods, by compensation methods or otherwise.