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Final Examination

Biophysics 5157 June 6, 1980

Open book examination to be completed and returned by 12:00 noon Monday, June 9, 1980. You may use any available references or your notes, but do not consult with other students or staff regarding questions or answers.

I. Present your VCRS analysis done on yourself with the original record on which it is based along with a brief (1 - 2 page) evaluation and commentary on it. It is desirable, but not in any sense required, that you evaluate and compare the “off” as well as the “on” strokes of the pulse record.

II. Suppose that you had available equipment that would accurately report the moment-by-moment direction of gaze of a human experimental subject's eyes. Design an experimental procedure utilizing this facility by which you could add to our understanding of pattern recognition by confirming or denying specific features of hypothesized internal sequencing of inspections for the purpose of pattern recognition. Be reasonably specific and indicate how many subjects and experimental repetitions would be needed to confirm your findings

III. Biological systems have developed and used, over and over again, in widely diversified forms, certain principles or strategies or “tricks” to great advantage. These tricks are likely to emerge as quantitatively expressible algorithmic biophysical principles as we get to understand them and, in turn, use them technically. These principles do not violate or invalidate ordinary physical or chemical “laws” but provide a new working set for life science and its technology. Provide your list of 5 to 7 candidates for inclusion in this list and explain why each is destined to become a utility principle or law as it becomes more perfectly formulated and understood.

IV. Explain in a compact sentence or two the following concepts with which, in their biophysical context, we have dealt in the last quarter.

1) contrast enhancement
2) conditioned stability
3) saccadic
4) CAT
5)
6) hierarchical control
7) Perceptron
8) Episodal
9) Autocorrelogram
10) Fourier Transform Coherency